Quick Comparison

Argan OilPetrolatum (Vaseline)
Typical ConcentrationApply 2-4 drops to damp or dry skin after water-based products. Can be used morning and night. For hair: apply to damp ends. Cold-pressed, cosmetic-grade oil preferred over culinary grade (which is roasted and has different properties).Apply thin layer over damp skin or over other skincare products. Can be used as 'slugging' (applying all over face at night). Safe for daily use. Especially effective over retinoids to buffer irritation.
ApplicationTopical (pure oil or in formulations). Apply as final step of skincare or mixed with moisturizer.Topical (ointment, lip balm). Apply as final step to seal in moisture. Thin layer is sufficient.
Research Papers10 papers10 papers
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Mechanism of Action

Argan Oil

Oleic acid (43-49%) and linoleic acid (29-36%) provide emollient and barrier-repair effects. Linoleic acid is component of ceramide 1 (acylceramide); acne-prone skin has been shown to have 50% less in sebum — topical supplementation may normalize follicular linoleate levels and reduce comedone formation. Oleic acid enhances penetration of other actives but can disrupt barrier in excess. Vitamin E (alpha-tocopherol) at 600-900 mg/kg provides antioxidant protection against lipid peroxidation. Squalene (6-8%) mimics skin's natural sebum composition. Polyphenols (ferulic acid, vanillic acid) provide additional antioxidant effects and may inhibit tyrosinase. Fatty acid profile supports lamellar body formation and ceramide synthesis in keratinocytes. Comedogenic rating 0-2. Cold-pressed oil retains tocopherols and polyphenols lost in refined versions.

Petrolatum (Vaseline)

Petrolatum is a mixture of long-chain saturated hydrocarbons (C16-C32) that forms a semi-occlusive film—reducing transepidermal water loss (TEWL) by up to 99%. It penetrates intercellular spaces of the stratum corneum, filling gaps in the lipid lamellae and creating a hydrophobic barrier. This occlusive environment raises stratum corneum water content, activating endogenous repair: upregulation of antimicrobial peptides (defensins, cathelicidin LL-37), lamellar body secretion, and barrier lipid synthesis. The stratum corneum obtains oxygen from dermal circulation, not the atmosphere. Studies demonstrate accelerated wound healing and barrier recovery, contradicting infection myths.

Risks & Safety

Argan Oil

Common

May cause breakouts in some acne-prone individuals despite relatively low comedogenic rating.

Serious

None.

Rare

Allergic reaction (tree nut allergy cross-reactivity is very rare but possible).

Petrolatum (Vaseline)

Common

Greasy feel. May trap bacteria if applied over unwashed skin (cleanse first).

Serious

None when using cosmetic-grade/USP petrolatum.

Rare

Allergic reaction is extremely rare. Concerns about contamination (PAHs) apply only to industrial-grade, not cosmetic-grade petrolatum.

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