Quick Comparison

Titanium DioxideTitanium Dioxide
Typical ConcentrationIn sunscreens: 2-15% concentration. Usually combined with zinc oxide. Apply 1/4 teaspoon for face. Reapply every 2 hours. Micronized forms significantly reduce white cast.In sunscreens: 2-15% concentration. Usually combined with zinc oxide. Apply 1/4 teaspoon for face. Reapply every 2 hours. Micronized forms significantly reduce white cast.
ApplicationTopical (sunscreen, tinted products). Apply liberally. Immediate protection upon application.Topical (sunscreen, tinted products). Apply liberally. Immediate protection upon application.
Research Papers10 papers10 papers
Categories

Mechanism of Action

Titanium Dioxide

Titanium dioxide (TiO2) absorbs, scatters, and reflects UV radiation through its semiconductor properties and high refractive index. It provides excellent UVB protection (280–320 nm) and short-wave UVA (UVA-II, 320–340 nm) protection, but exhibits a band-gap that limits efficacy against long-wave UVA (UVA-I, 340–400 nm). This spectral gap is why titanium dioxide is typically combined with zinc oxide in mineral sunscreens for comprehensive coverage. Like zinc oxide, titanium dioxide is photostable—it does not degrade or isomerize with UV exposure, unlike some organic filters. Micronized and nano forms reduce white cast while maintaining efficacy. Titanium dioxide particles remain on the skin surface and do not penetrate intact stratum corneum. Uncoated nano TiO2 can generate reactive oxygen species (ROS) under UV; surface coatings (silica, alumina) mitigate this. Clinically, it is well-tolerated and non-comedogenic.

Titanium Dioxide

Titanium dioxide (TiO2) absorbs, scatters, and reflects UV radiation through its semiconductor properties and high refractive index. It provides excellent UVB protection (280–320 nm) and short-wave UVA (UVA-II, 320–340 nm) protection, but exhibits a band-gap that limits efficacy against long-wave UVA (UVA-I, 340–400 nm). This spectral gap is why titanium dioxide is typically combined with zinc oxide in mineral sunscreens for comprehensive coverage. Like zinc oxide, titanium dioxide is photostable—it does not degrade or isomerize with UV exposure, unlike some organic filters. Micronized and nano forms reduce white cast while maintaining efficacy. Titanium dioxide particles remain on the skin surface and do not penetrate intact stratum corneum. Uncoated nano TiO2 can generate reactive oxygen species (ROS) under UV; surface coatings (silica, alumina) mitigate this. Clinically, it is well-tolerated and non-comedogenic.

Risks & Safety

Titanium Dioxide

Common

White cast (less than zinc oxide). Potential for drying in very dry skin types.

Serious

Same nano-particle debate as zinc oxide — current evidence shows no systemic absorption through intact skin.

Rare

Inhalation concern with spray/powder sunscreens (avoid inhaling).

Titanium Dioxide

Common

White cast (less than zinc oxide). Potential for drying in very dry skin types.

Serious

Same nano-particle debate as zinc oxide — current evidence shows no systemic absorption through intact skin.

Rare

Inhalation concern with spray/powder sunscreens (avoid inhaling).

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